cover-19

Thursday May 20, 2021

Editorial Cartoon by Graeme MacKay, The Hamilton Spectator – Thursday May 20, 2021

Vaccination Patriotism

Ten thousand shots was the hope. The result was 10,470. That’s how many doses of COVID-19 vaccine were administered at an immunization clinic at the Thorncliffe Park Community Hub in Toronto on Sunday. Until well after dark, long lines snaked through the parking lot, where people were entertained by DJs before entering the cavernous site. By the end of the day, the clinic, run by more than 50 local community and health care organizations, set a record for the most shots administered at one location on a single day. That record-breaking day in Toronto is a reason why Canada is about to surpass the United States—likely on Thursday—when it comes to the percentage of population with first doses. Right now, Canada has given first doses to 44.7 per cent of its population. In the United States, it’s 47.3 per cent. 

March 31, 2021

First doses is an important metric, for not only do first doses slow the spread of COVID-19 within communities but they are “a sign of people’s willingness to get vaccinated,” says Trevor Tombe, an associate professor of economics at the University of Calgary who provides daily updates on Canada’s vaccine progress on his Twitter feed as well as his GitHub page. “You can’t get your second shot unless you’ve got your first. And so measuring how many people are willing to get their first shot tells us the state of demand for vaccines in Canada.” 

This week alone, Canada will receive 4.5 million doses of Pfizer and Moderna vaccine (Pfizer moved up next week’s delivery because of the Victoria Day long weekend). And that has allowed provinces to open the vaccine appointment spigot even wider: As of May 18, everyone aged 18 and older in Ontario can book a time to get their shot on the provincial system. 

March 4, 2021

This ramp-up in Canada’s vaccine rollout has been a long time coming. On March 1, vaccine deliveries were so small that Canada wasn’t on pace to reach 75 per cent of its population having first doses until Nov. 24, 2022. Then, vaccine supply accelerated in April and May. Now, at our current pace, Tombe’s model suggests that Canada should reach 75 per cent by June 19. In addition, 75 per cent of all eligible Canadians 12 and up could have second doses by the second week in August. 

Any comparison with the United States interests Canadians. On April 9, when Canada’s per capita rate of new cases surpassed that of the United States for the first time, there were rumblings about what went wrong—Canada’s third wave was intensifying while the United States was seeing a long-term drop in cases as its vaccination effort was yielding results. While Canada’s rate of new cases has improved from the 205 per million population on April 9, the U.S. has dropped even faster. As of May 16, Canada posted a seven-day average of 160 per million while the U.S. is at 100. 

March 13, 2021

But the United States is struggling with the concerning issue of vaccine hesitancy. A late-April poll showed that around a quarter of adults in the U.S. don’t want to get a shot. In Canada, only nine per cent say they won’t get the vaccine compared to 88 per cent who either will or have received a dose, according to a new Angus Reid poll, which bodes well for Canada achieving herd immunity. (Maclean’s)  

Meanwhile, The world has reached a situation of “vaccine apartheid”, World Health Organization Director-General Tedros Adhanom Ghebreyesus said on Monday, and was no longer just at risk of that status. “The big problem is a lack of sharing. So the solution is more sharing,” he told a virtual Paris Peace Forum event. (Reuters) 

April 28, 2021

Also, An international humanitarian group is calling on the Canadian government to commit to sharing its COVID-19 vaccine supply, at a time when other low- and middle-income countries are falling behind on inoculation.

May 11, 2021

The medical non-profit group Doctors Without Borders is asking Ottawa to stop accepting vaccine supply from COVAX, the global pool procurement mechanism for COVID-19 vaccines. It recently announced that it’s short at least 140 million doses, in part because of the ongoing COVID-19 crisis in India. The World Health Organization, UNICEF and other international agencies have called on G7 countries to donate excess vaccine supplies. While countries like the United States and France have announced plans to donate millions of doses, Canada has yet to make such an announcement. In the meantime, it’s continuing to receive COVID-19 doses from COVAX, with 600,000 doses of AstraZeneca that arrived last week, and more expected by the end of June. (Yahoo News) 

 

Wednesday May 12, 2021

Editorial Cartoon by Graeme MacKay, The Hamilton Spectator – Wednesday May 12, 2021

What happens when people get two different COVID-19 vaccines?

As some experts continue to warn of very rare side effects associated with the AstraZeneca vaccine, Canadian health officials are now reviewing the research on mixing various COVID-19 shots.

May 6, 2020

A study of a “mismatched” vaccine regimen is underway in the U.K. — but some scientists say there’s reason to believe that administering two doses of different products could boost a person’s immune response beyond what can be achieved by giving the same shot twice.

The National Advisory Committee on Immunization (NACI) caused some confusion earlier this month when it said the viral vector shot from AstraZeneca is not the “preferred” product given its associated risk of vaccine-induced immune thrombotic thrombocytopenia (VITT) — a condition that causes blood clots. That warning came out after hundreds of thousands of Canadians had received the AstraZeneca vaccine already.

According to the Ontario Science Table, estimates of the frequency of VITT in individuals who have received the AstraZeneca vaccine now range from 1 case in 26,000 to 1 case in 127,000 doses administered.

The risk of developing this side effect, combined with an uncertain delivery schedule for future supply, has prompted some provinces to consider pausing AstraZeneca vaccinations altogether.

Researchers at Oxford University in the U.K. launched a study in early February to explore the possible benefits of alternating different COVID-19 vaccines. According to the lead scientists, the study is “looking for clues as to how to increase the breadth of protection against new virus strains.”

March 31, 2021

The study — otherwise known as the COVID-19 Heterologous Prime Boost study, or “Com-COV” — is collecting data to determine whether receiving two different types of vaccine generates an immune response at least equal to the response that follows receiving the same product twice. (A “heterologous” vaccination regimen is one that uses more than one product.)

Dr. Helen Fletcher is a professor of immunology at the London School of Hygiene and Tropical Medicine in the U.K. She said a “mismatched” vaccine program would deliver some practical benefits — vaccine delivery logistics would be greatly simplified — but there could be another good reason to pursue a mixed-dose regimen.

“I’m excited about the study because I think it’s likely that the immune response will be even better if you mix and match vaccines,” Fletcher said in an interview with CBC News.

Dr. Theresa Tam, Canada’s chief public health officer, said last week the current guidance is for AstraZeneca recipients to get a second dose of the same product, but NACI is now reviewing the Oxford research on mixing AstraZeneca with an mRNA shot.

“There will be further advice forthcoming on that second dose based on the evolving science. We should watch this space,” Tam said. 

Will Canada shorten the time between shots? Possibly. NACI said in early March that, given the limited vaccine supply, provinces and territories may want to wait up to 16 weeks between first and second doses to give more people at least some level of protection.

The provinces have since followed this guidance, with a few exceptions. For example, many long-term care home residents have been fully vaccinated on the timeline recommended by the vaccine makers. Pfizer calls for a second dose 21 days after the first, while Moderna stipulates the second shot should come 28 days later. (CBC) 

 

 

Tuesday May 11, 2021

Editorial Cartoon by Graeme MacKay, The Hamilton Spectator – Tuesday May 11, 2021

Poorer countries might not get vaccinated until 2023

High-income countries have purchased more than half of the Covid-19 vaccine supply to date, and low-income countries, just 9 percent, according to Duke University’s Global Health Innovation Center. This is why a country like the US is close to vaccinating half its population with one dose while the rate in a place like Guinea is less than 1 percent and not budging.

October 27, 2021

If these glaring inequities in vaccine access continue, it will take at least two years for the world’s poorest countries, which couldn’t afford to compete for early doses of vaccines, to immunize the majority of their populations. And we’re on track for a long period where people in rich countries enjoy the benefits and safety of being fully immunized, while people in poorer countries continue to get sick and die from the coronavirus. 

“That’s not just unconscionable, but it also is very much against the interests of high-income countries,” Georgetown global health law professor Lawrence Gostin told Vox in January. With the virus continuing to circulate, and variants picking up pace around the globe, outbreaks in the poorest countries will pose a threat to the world. 

It’s not an accident that many of the world’s first-approved Covid-19 vaccines — from companies like Pfizer, AstraZeneca, and Moderna — were developed and rolled out in high-income countries. As the pandemic took hold last year, wealthier nations — including the US, UK, and EU block — began making deals with the pharmaceutical companies that were developing Covid-19 vaccines, which also happened to be headquartered within their borders.

January 28, 2021

These bilateral deals involved governments essentially giving the companies billions of dollars to speed up research and development in exchange for priority access to vaccines, should they prove to be effective. But the deals also pushed poorer countries, which didn’t have the resources to pre-purchase millions of doses of vaccines that might not even get approved for market, further down the access line.

Rich countries could donate more doses to poorer countries — a move global health groups have been calling for for months and one that’s starting to happen in response to the crisis in India. 

Rich countries could also simply start investing more in helping poorer countries respond to the crisis. They could answer Covax’s call for more donor funds, for example. Or Omer called for something akin to PEPFAR, America’s global health program to combat AIDS around the world. Launched under George W. Bush in 2003, to date, it’s provided $90 billion toward fighting AIDS. (Vox) 

 

Wednesday January 6, 2020

January 6, 2020

Editorial Cartoon by Graeme MacKay, The Hamilton Spectator – Wednesday January 6, 2020

Don’t lump all politicians in with scofflaws

Reading Spectator journalist Katrina Clarke’s report surveying local politicians about their activities over Christmas, you may have been struck first by the fact that one Hamilton-area politician did indeed travel.

Veteran Conservative Flamborough-Glanbrook MP David Sweet acknowledged to his leader’s office that he travelled to the U.S., first on business to deal with a “property issue,” and then later “for leisure.” But Erin O’Toole’s office didn’t know about the “leisure” part. Sweet “resigned” from chairing — of all things — the House of Commons Ethics Committee, the leader’s office reported Monday. And he has said he will not run again in the next federal election. Sweet remains in the U.S. at this point. 

O’Toole had requested, explicitly, that caucus members not take part in international travel over the Christmas holidays, so it’s little wonder Sweet’s career as a Conservative MP was quickly declared dead in the water. It’s an ignominious way to end a 15-year-career in politics. Twitter lit up with reaction, much of it lauding Sweet for his work but even more of it bitterly critical, such as John P. Soleas, who Tweeted: “Why are you still out of the country? You should’ve been flying back yesterday! Your constituents are staying home and abiding by public health guidance. If you can’t stay in the country when it counts why not resign today and relieve yourself of this heavy burden?”

Sweet and other politicians caught up in this angry storm are learning the hard way: This is no minor bit of bad behaviour. Travelling while the rest of Canada is locked down and suffering has tapped a vein of outrage and hurt. Read the letters from Spec readers and others across the country. Read about broken-hearted families who wanted desperately to see each other but couldn’t due to the travel guidelines. Parents of adult children who always see their kids and grandkids at Christmas, but couldn’t this year. People who lost loved ones before or during the pandemic and could not be with relatives for comfort and consolation. People who are used to gathering with families who had to settle for the Zoom equivalent this holiday season.

The collective reaction is not annoyance at the display, yet again, of a double standard between “them” and the rest of us. It’s more like the reaction of people who feel they have been attacked and wounded. Is it entirely reasonable? You can argue either way, but it is what it is. Public reaction on this issue is like a force of nature, and it won’t be dismissed or managed, as so many Canadian politicians have learned.

But here is something else worth considering. For the story mentioned earlier Clarke got responses from something like 20 area politicians, local, provincial and federal. (Several others have yet to respond.) But if they’re all being honest — and they would be very foolish at this point to be anything but forthright — the rest of them spent their holidays season the same way the majority of us did.

They spent Christmas and New Year’s alone, or Zoomed with friends and family. They hosted small outdoor gatherings, masked and distanced. Some had “garage gatherings” which in our view is questionable, but for the most part these elected officials are living with the same public health guidelines we all are.

As we survive this latest pandemic outrage, it is important that we make it entirely clear we expect those elected to represent and serve us to abide by the same rules they levy upon us. And to use common sense. But we should also be careful not to lump all politicians together with those who have abused the public trust. Most are playing by the rules, and the few who are not are paying the price. (Hamilton Spectator Editorial) 

 

Saturday November 21, 2020

Editorial Cartoon by Graeme MacKay, The Hamilton Spectator – Saturday November 21, 2020

Why Trump’s Operation Warp Speed is credited with helping race for COVID-19 vaccine

Operation Warp Speed, a Trump administration initiative to manufacture COVID-19 vaccines as fast as possible, should be lauded as a successful endeavour in what has otherwise been a poor effort to deal with the coronavirus, experts say.

September 10, 2020

“No doubt, Operation Warp Speed is a huge success,” said Tinglong Dai, associate professor of Operations Management and Business Analytics at Johns Hopkins University Carey Business School in Baltimore.

“You can like or hate the Trump administration, but no doubt, it’s a huge success — unprecedented success.”

Jesse Goodman, the former chief scientist of the U.S. Food and Drug Administration, agreed that the U.S. government deserves credit for the high priority placed on Operation Warp Speed.

“This is a bright spot in the pandemic response. I mean, the rest of it has been dismal,” said Goodman, who is also director of Georgetown University’s Center on Medical Product Access, Safety and Stewardship.

Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases, also lauded Operation Warp Speed for being a “success — certainly in the arena of vaccines, it’s been a success” in his remarks at a recent virtual summit organized by the medical news site Stat.

November 14, 2020

Launched in May, Operation Warp Speed (OWS) is a government initiated private/public $10 billion US program to help provide support to companies in the development, manufacturing and distribution of 300 million doses of COVID-19 vaccine, with the aim of having initial doses ready by January 2021. 

Allison Winnike, president of the Texas-based Immunization Partnership, an organization providing advocacy and information about immunization initiatives, said that Moderna benefited tremendously from Operation Warp Speed, in part, by receiving close to $1 billion to support its vaccine development and clinical trials.

As for the role the funding played in the development of Pfizer’s vaccine, that’s a bit fuzzier. Last week, when the company announced it had developed a vaccine that was more than 90 per cent effective, U.S. President Donald Trump said that Pfizer was suggesting “it wasn’t part of Warp Speed, but that turned out to be an unfortunate misrepresentation.” (CBC News)